Aldehyde dehydrogenase activity of Wharton jelly mesenchymal stromal cells: isolation and characterization
نویسندگان
چکیده
منابع مشابه
Discarded Wharton jelly of the human umbilical cord: a viable source for mesenchymal stromal cells.
Mesenchymal stromal cells (MSCs) are multi-potent cells that have the capability of differentiating into adipogenic, osteogenic, chondrogenic and neural cells. With these multiple capabilities, MSCs have been highly regarded as an effective transplantable cell source for regenerative medicine. A large bank of these cells can be found in several regions of the human umbilical cord, including the...
متن کاملReduced aldehyde dehydrogenase expression in preeclamptic decidual mesenchymal stem/stromal cells is restored by aldehyde dehydrogenase agonists
High resistance to oxidative stress is a common feature of mesenchymal stem/stromal cells (MSC) and is associated with higher cell survival and ability to respond to oxidative damage. Aldehyde dehydrogenase (ALDH) activity is a candidate "universal" marker for stem cells. ALDH expression was significantly lower in decidual MSC (DMSC) isolated from preeclamptic (PE) patients. ALDH gene knockdown...
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OBJECTIVE Mesenchymal stromal cells (MSCs) are considered as an excellent source in regenerative medicine, but availability and ethical problems limited their routine use. Therefore, another available source with easy procedure and exempt from ethical debate is important. The purpose of this study is to isolate and characterize the MSCs from human placenta. The stromal cells were isolated from ...
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Fetal and adult stem cells have the potential to play vital role in livestock production and management. Fetal stem cells in comparison to stem cells from other sources are easily accessible and can be isolated in larger quantities. Additionally it can provide new insights into development biology of animals. Fetal stem cells may develop as a valuable source of stem cells for clinical applicati...
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Background: The number of patients suffering from diabetic ulcers has been increased in recent years and the current therapies have faced failure. This study aimed to investigate the effects of Wharton’s jelly stem cells (WJMSCs) on the diabetic wound in an animal mode. Methods: During this laboratory experimental study carried out in Skin and Stem Cells Research Center from March 2021 to Nove...
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ژورنال
عنوان ژورنال: Cytotechnology
سال: 2019
ISSN: 0920-9069,1573-0778
DOI: 10.1007/s10616-018-0283-8